Phase I study of afatinib and radiotherapy with or without temozolomide in newly diagnosed glioblastoma
Frank Saran, Liam Welsh, Allan James, Catherine McBain, Sarah Jefferies, Fiona Harris, Agnieszka Cseh, Karine Pemberton, Jennifer Schaible, Shaun Bender, Michael Brada
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In the European Union, afatinib is approved for use in TKI-naive adults with locally advanced or metastatic NSCLC with activating EGFR mutations and in patients with NSCLC of squamous histology on or after chemotherapy. It is not yet approved in other indications.
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