WCLC - Nowak Presentation

Nintedanib + pemetrexed/cisplatin in malignant pleural mesothelioma: Phase II biomarker data from the LUME-Meso study

Nowak K, Grosso F, Steele N, Novello S, Popat S, Greillier L, John T, Leighl N, Reck M, Pavlakis N, Sørensen J, Planchard D, Ceresoli G, Hughes B, Mazières J, Socinski M, Salnikov A, Kitzing T, Braunger J, Pietzko K, Scagliotti G


Learn more about the science behind this presentation in the papers and other materials below


Nintedanib plus pemetrexed/cisplatin in patients with malignant pleural mesothelioma: Phase II results from the randomized, placebo-controlled LUME-Meso trial

Grosso F et al. JCO 2017; DOI: 10.1200/JCO.2017.72.9012

LUME-Meso: design and rationale of the Phase III part of a placebo-controlled study of nintedanib and pemetrexed/cisplatin followed by maintenance nintedanib in patients with unresectable malignant pleural mesothelioma

Scagliotti G et al. CLC 2017; DOI: 10.1016/j.cllc.2017.03.010

Nintedanib is being investigated in malignant pleural mesothelioma (MPM) and is not approved for this use. The efficacy and safety of nintedanib in MPM have not been established.